Overview
PackGene offers custom inhibitory miRNA AAV vectors that can be used to inhibit endogenous miRNA expression and function in live animals.
miRNA are small non-coding RNAs that are endogenously expressed in eukaryotes and play important role in regulating gene expression. miRNA inhibitors are RNA molecules that are designed as reverse compliment sequence to endogenous miRNA and functionally block their gene regulation capabilities.
Direct, convenient, and efficient expression of miRNA inhibitors for in vivo animal experiments
Ability to target various organs and tissues through specific AAV serotypes
Geater expression durability and longer effect duration when compared to traditional synthetic miRNA inhibitors
Increased safety and immunogenicity relative to traditional synthetic miRNA inhibitors
Related Services / Products
AAV Packaging Services
Ranging from pilot to industrial-scale AAV packaging for both in vitro and in vivo studies.
READ MORE
AAV Analytical Services
We are one of the few vendors that can do ALL in-house.
READ MORE
Off the Shelf AAV Products
We offer a wide catalogue of pre-made AAVs for a multitude of research needs.
READ MORE